CLOTRIMAZOLE AND BETAMETHASONE DIPROPIONATE SKIN

Those with broken skin barrier or extensive abrasions.Those who have used corticosteroids to cover a large surface area.Those who have used topical corticosteroids over a prolonged period of time.

Those at increased risk for HPA axis suppression are those who are more likely to absorb more of the steroid through the skin. Symptoms of HPA axis suppression are often subtle and variable, but can often be detected using simple blood or urine tests such at ACTH stimulation test or urinary free cortisol. This can lead to a depression in the release of adrenal hormones such as cortisol and adrenocorticotropic hormone, or ACTH. One such effect is the ability of the corticosteroid to suppress the hypothalamic–pituitary–adrenal axis. Adverse effects Īlthough the absorption of betamethasone dipropionate is small, when used for prolonged periods of time (periods exceeding two weeks), or across a large surface area (total use greater than 50 grams per week), it can have adverse effects. Although its exact mechanism of action is not known, it is effective when applied topically to cortico-responsive inflammatory dermatoses. It is a synthetic analog of the adrenal corticosteroids. Betamethasone dipropionate is a 'super high potency' corticosteroid used to treat inflammatory skin conditions such as dermatitis, eczema and psoriasis. Minor side effects include dry skin and mild, temporary stinging when applied.

It is applied as a topical cream, ointment, lotion or gel ( Diprolene) to treat itching and other skin conditions such as eczema. Betamethasone dipropionate is a glucocorticoid steroid with anti-inflammatory and immunosuppressive abilities.

Clotrimazole and betamethasone dipropionate